Literature Survey
spacer.gif (877 bytes)
spacer.gif (877 bytes)
Home Up Contents Search Feedback Contact TAIspacer.gif (877 bytes)spacer.gif (877 bytes)

Medical Benefits of the ERGYS and REGYS FES Leg-Cycle Ergometers:

A Survey of Published Clinical Studies

Therapeutic Alliances will strive to continually improve this bibliography by adding references, links, etc. If your paper is not referenced here, please forgive us for the omission. We invite you to send us an EMAIL providing the title, authors, publication name, date and pages, and an abstract.

Contact the Editor

For other literature searches provided free of charge:

MEDLINE - National Library of Medicine and MEDLINE Experimental Search Engine

Janssen T. W. J., Glaser R. M., Shuster D. B.: Clinical Efficacy of Electrical Stimulation Exercise Training: Effects on Health, Fitness, and Function. Topics in Spinal Cord Injury Rehabilitation (Stephen Figoni, issue editor; David Apple, editor): Winter 1998, An Aspen Publication.

Conclusion: The collection of research strongly suggests that lower limb FES-induced exercise training can offer multiple therapeutic benefits for individuals with SCI.


Mohr T., Andersen J., Biering-Sorensen F., Henrik G., Bangsbo J., Wagner A., Kjaer M.: Long term adaptation to electrically induced cycle training in severe spinal cord injured individuals. Spinal Cord: Vol. 35: 1-16, 1997.

 Conclusion: One year of electrically induced cycle training can reverse several of the inactivity associated changes seen after SCI. Among the changes noted were a 12% growth in the stimulated muscle and a six-fold work performance increase accompanied by a 23% increase in maximal oxygen uptake. [REGYS]


Nash M. S., Montalvo B. M., Applegate B.: Lower extremity blood flow and responses to occlusion ischemia differ in exercise-trained and sedentary tetraplegic persons. Archives of Physical Medicine and Rehabilitation: Vol. 77: 1260-1265, 1996.

 Conclusion: Tetraplegic persons conditioned by electrically stimulated cycling have greater lower extremity blood flow and hyperemic responses to occlusion than do their sedentary counterparts. [ERGYS]


Hooker S. P., Scremin E., Mutton D. L., Kunkel C. F., Cagle G: Peak and submaximal physiologic responses following electrical stimulation leg cycle ergometer training. Journal of Rehabilitation Research and Development: Vol. 32, No. 4: 361-366, 1995.

 Conclusion: Two-time per week NMES leg cycle training program will also result in significant increases in exercise tolerance and cardiorespiratory capacity in persons with SCI (compared with three times per week). [REGYS]


Twist, D. J., Culpepper-Morgan J. A., Ragnarsson K. T., Petrillo C. R., Kreck M. J. Neuroendocrine changes during functional electrical stimulation. American Journal of Physical Medicine and Rehabilitation: 71: 156-163, 1992.

 Conclusion: 30 weeks of FNS exercise training led to significant increases in beta endorphin-like immunoreactivity, improved regulation of cortisol, and improved scores on a depression index. [REGYS, ERGYS]


Nash M. S., Bilsker S., Marcillo A. E., Isaac B. S., Botelho L. A., Klose K. J., Green B. A., Rountree M. T., Shea J. D. Reversal of left ventricular atrophy following electrically-stimulated exercise training in human tetraplegics. Paraplegia 29: 590-599, 1991.

 Conclusion: Six months of exercise led to significant increases in left ventricular internal dimension and intraventricular septal and posterior wall thicknesses in quadriplegics. [ERGYS]


Kristjan T. Ragnarsson, Susan Pollack Feldman, Donna Twist. Lower limb endurance exercise after spinal cord injury: implications for health and functional ambulation. J Neuro Rehab 1991;5:37-48.

Conclusion: When the lower motor neuron system is intact, paraplegics and quadriplegics can perform substatial exercise through the use of computerized functional electrical stimulation. Many of the effects of physical inactivity experienced after SCI may be reversed by FES intervention. [REGYS, ERGYS]


Steven P. Hooker, Stephen F. Figoni, Roger M. Glaser, Mary M. Rodgers, Bertram N. Ezenwa, Pouran D. Faghri. Physiologic responses to prolonged electrically stimulated leg-cycle exercise in the spinal cord injured. Archives of Physical Medicine and Rehabilitation: Vol. 71: 863-869, 1990.

Conclusion: Despite the existence of sympathetic impairment, 30 minutes of FES leg-cycle exercise in a controlled environment does not result in inappropriate physiologic responses in SCI individuals. [ERGYS]


Sipski M. L., Delisa J. A., Schweer S. Functional electrical stimulation bicycle ergometry: patient perceptions. American Journal of Physical Medicine and Rehabilitation: 68: 147-149, 1989.

 Conclusion: A majority of SCI subjects indicated improved self-image and perceived their appearance to be better following training. [ERGYS]

Therapeutic Alliances Inc.
333 North Broad Street - Fairborn, OH 45324  USA
(937) 879-0734 - (937) 879-5211 (fax)

This page and all Therapeutic Alliances-designed link pages are Copyright 1996-2012 Therapeutic Alliances Incorporated, Fairborn, Ohio USA. All rights reserved. Therapeutic Alliances Inc., ERGYS®, REGYS, SpectraSTIM®, NeuroEDUCATOR®, Stimwear®, "You Are the Moving Part," and "The Power of Your Muscles" are trademarks of Therapeutic Alliances Inc. Control Bionics and NeuroSwitch are trademarks of Control Bionics Inc. Parastep is a trademark of Sigmedics Inc.

Send mail to with questions or comments about this web site.